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制霉菌素A、B和C：新型抗真菌抗生素。I. 分类学、生产、分离及理化性质

Pradimicins A, B and C: new antifungal antibiotics. I. Taxonomy, production, isolation and physico-chemical properties.

作者信息

Tomita K, Nishio M, Saitoh K, Yamamoto H, Hoshino Y, Ohkuma H, Konishi M, Miyaki T, Oki T

机构信息

Bristol-Myers Research Institute, Ltd., Tokyo Research Center, Japan.

出版信息

J Antibiot (Tokyo). 1990 Jul;43(7):755-62. doi: 10.7164/antibiotics.43.755.

DOI:10.7164/antibiotics.43.755
PMID:2387769
Abstract

New antifungal antibiotics, pradimicins A, B and C were isolated from the culture broth of actinomycete strains proposed as Actinomadura hibisca. They are orange to red pigments containing a benzo[a]naphthacenequinone chromophore substituted with a D-alanine, an aminosugar and a D-xylose (pradimicins A and C).

摘要

新型抗真菌抗生素普拉地米星A、B和C是从被认为是 Hibisca马杜拉放线菌的放线菌菌株的培养液中分离出来的。它们是橙色至红色的色素，含有一个被D-丙氨酸、一个氨基糖和一个D-木糖取代的苯并[a]萘并醌发色团（普拉地米星A和C）。

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