Han Zhao-Yu, Wang Gen-Lin, Chen Wen, Zhang Li-Jun
College of Animal Science & Technology, Nanjing Agricultural University, Nanjing, Jiangsu 210095, China.
Zhonghua Nan Ke Xue. 2003 Nov;9(8):566-8.
To evaluate the effects of daidzein on sperm quality of male mice.
Three different doses of daidzein were supplemented to pubertal male mice for 21 days(5 mg/kg, 100 mg/kg, 1,000 mg/kg ration). The viability of sperm was determined by eosin-Y, the acrosome was observed by Wright-Giemsa staining, and the testosterone was measured by radioimmunoassay.
Daidzein at the dose of 5 mg/kg ration significantly increased serum testosterone levels (P < 0.01), prompted testis gain (P < 0.05), and improved spermatozoa quality. Daidzein at dose of 1,000 mg/kg ration could inhibit the secretion of serum testosterone (P < 0.01), without significant variation in spermatozoa quality. Daidzein at dose of 100 mg/kg ration did not significantly affect sperm quality and other index.
Daidzein can affect sperm quality and in dosage-dependant ways.
