Sliwa L, Macura B
Department of Human Developmental Biology, Collegium Medicum, Jagiellonian University, Kraków, Poland.
Arch Androl. 2005 Nov-Dec;51(6):443-8. doi: 10.1080/014850190953221.
The functional integrity of the cell membrane of the mice sperm after daidzein administration intraperitoneal was assessed by studying the swelling reaction of the sperm when suspended in distilled water. The results obtained in water test indicate that daidzein, one of the phytoestrogens, decreases the number of normal and live sperm (swollen) in the samples obtaining from vas deferens. This effect was statistically significant in the mice after 7 and 14 days of daidzein administration. In mice treated with daidzein the number of dead (unswollen) sperm was increased, especially in animals after 14 days of experiment.
通过研究小鼠精子悬浮于蒸馏水中的肿胀反应，评估腹腔注射大豆苷元后小鼠精子细胞膜的功能完整性。水试验结果表明，植物雌激素之一的大豆苷元可减少从输精管获取的样本中正常活精子（肿胀的）数量。在给予大豆苷元7天和14天后的小鼠中，这种效应具有统计学意义。用大豆苷元处理的小鼠中，死精子（未肿胀的）数量增加，尤其是在实验14天后的动物中。
