The exocytotic fusion pore.
作者信息
Monck J R, Fernandez J M
机构信息
Department of Physiology and Biophysics, Mayo Clinic, Rochester, Minnesota 55905.
出版信息
J Cell Biol. 1992 Dec;119(6):1395-404. doi: 10.1083/jcb.119.6.1395.
Abstract
摘要
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The exocytotic fusion pore.胞吐融合孔
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Relationship between fusion pore opening and release during mast cell exocytosis studied with patch amperometry.采用膜片钳安培法研究肥大细胞胞吐过程中融合孔开放与释放之间的关系。
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Is the activity of the fusion pore scaffold regulated by a coincidence detector?融合孔支架的活性是否由一个巧合探测器调节？
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The fusion pore.融合孔。
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Hydrophobic ions amplify the capacitive currents used to measure exocytotic fusion.疏水性离子会放大用于测量胞吐融合的电容电流。
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Patch clamp studies of single intact secretory granules.单个完整分泌颗粒的膜片钳研究。
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Complexin II facilitates exocytotic release in mast cells by enhancing Ca2+ sensitivity of the fusion process.复合体II通过增强融合过程对钙离子的敏感性来促进肥大细胞中的胞吐释放。
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Cell physiology. Secretion without full fusion.细胞生理学。不完全融合的分泌。
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Simultaneous electrical and optical measurements of individual membrane fusion events during exocytosis.胞吐过程中单个膜融合事件的同步电学和光学测量。
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New Biophysical Approaches Reveal the Dynamics and Mechanics of Type I Viral Fusion Machinery and Their Interplay with Membranes.新的生物物理方法揭示了 I 型病毒融合机制的动力学和力学特性及其与膜的相互作用。
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The fusion pore, 60 years after the first cartoon.融合孔：第一张卡通画诞生 60 年后
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Cholesterol Increases the Openness of SNARE-Mediated Flickering Fusion Pores.胆固醇增加SNARE介导的闪烁融合孔的开放度。
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The neuronal porosome complex in health and disease.健康与疾病中的神经元孔体复合物
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'Porosome' discovered nearly 20 years ago provides molecular insights into the kiss-and-run mechanism of cell secretion.近20年前发现的“孔体”为细胞分泌的亲吻-逃离机制提供了分子层面的见解。
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SNARE and regulatory proteins induce local membrane protrusions to prime docked vesicles for fast calcium-triggered fusion.SNARE 和调节蛋白诱导局部膜突，使停靠的囊泡为快速钙触发融合做好准备。
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本文引用的文献
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Forces between surfaces in liquids.液体表面之间的力。
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Arrest of membrane fusion events in mast cells by quick-freezing.通过快速冷冻阻止肥大细胞膜融合事件。
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Beginning of exocytosis captured by rapid-freezing of Limulus amebocytes.通过快速冷冻鲎变形细胞捕捉到的胞吐作用起始过程。
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Interacting phospholipid bilayers: measured forces and induced structural changes.相互作用的磷脂双层：测量的力和诱导的结构变化。
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Discrete changes of cell membrane capacitance observed under conditions of enhanced secretion in bovine adrenal chromaffin cells.在牛肾上腺嗜铬细胞分泌增强的条件下观察到的细胞膜电容的离散变化。
Proc Natl Acad Sci U S A. 1982 Nov;79(21):6712-6. doi: 10.1073/pnas.79.21.6712.
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Freeze-fracture studies of chemotactic peptide-induced exocytosis in neutrophils: evidence for two patterns of secretory granule fusion.
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7
Membrane events in adrenal chromaffin cells during exocytosis: a freeze-etching analysis after rapid cryofixation.胞吐作用期间肾上腺嗜铬细胞中的膜事件：快速冷冻固定后的冷冻蚀刻分析。
Eur J Cell Biol. 1983 Nov;32(1):31-7.
8
On the theory of membrane fusion. The stalk mechanism.关于膜融合理论。茎干机制。
Gen Physiol Biophys. 1984 Oct;3(5):361-77.
9
Capacitance measurements reveal stepwise fusion events in degranulating mast cells.电容测量揭示了脱颗粒肥大细胞中的逐步融合事件。
Nature. 1984;312(5993):453-5. doi: 10.1038/312453a0.
10
Protein rotational diffusion and lipid structure of reconstituted systems of Ca2+-activated adenosine triphosphatase.
J Mol Biol. 1980 Aug 5;141(2):119-32. doi: 10.1016/0022-2836(80)90380-0.
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