Zhang Jianjun, Zhao Zijin, Berkel Hans J
Hipple Cancer Research Center, Dayton, OH 45439, USA.
Nutr Cancer. 2003;46(2):158-65. doi: 10.1207/S15327914NC4602_08.
The relation between egg consumption and mortality from colon and rectal cancers remains unclear and was investigated in this study. Colon and rectal cancer mortality data, mostly around 1993-94 and egg consumption data in nine time periods (1964-94) in 34 countries were derived from World Health Organization and Food and Agriculture Organization, respectively. Egg consumption was significantly and positively correlated with mortality from colon and rectal cancers in both sexes in most of the nine time periods. The correlations were generally stronger for colon cancer (r = 0.39 to 0.63 in men and r = 0.33 to 0.65 in women) than for rectal cancer (r = 0.18 to 0.49 in men and r = 0.08 to 0.45 in women). After adjustment for confounding factors, egg consumption was still significantly and positively associated with mortality from colon cancer in the earliest five time periods (1964-84) (P = 0.046 to 0.017 in men and P = 0.034 to 0.014 in women) and rectal cancer in the latest five time periods except for the last time period (1982-91) (P = 0.046 to 0.024 in men and P = 0.045 to 0.026 in women). This study suggested that egg consumption was associated with an increased risk of colon and rectal cancers at the population level
鸡蛋摄入量与结肠癌和直肠癌死亡率之间的关系尚不清楚，本研究对此进行了调查。结肠癌和直肠癌死亡率数据（大多为1993 - 1994年前后的数据）以及34个国家九个时间段（1964 - 1994年）的鸡蛋摄入量数据分别来自世界卫生组织和联合国粮食及农业组织。在九个时间段中的大多数时间段，鸡蛋摄入量与男女结肠癌和直肠癌死亡率均呈显著正相关。结肠癌的相关性通常比直肠癌更强（男性r = 0.39至0.63，女性r = 0.33至0.65），而直肠癌的相关性为男性r = 0.18至0.49，女性r = 0.08至0.45。在对混杂因素进行调整后，在最早的五个时间段（1964 - 1984年），鸡蛋摄入量仍与结肠癌死亡率显著正相关（男性P = 0.046至0.017，女性P = 0.034至0.014），在除最后一个时间段（1982 - 1991年）外的最后五个时间段与直肠癌死亡率显著正相关（男性P = 0.046至0.024，女性P = 0.045至0.026）。本研究表明，在人群层面，鸡蛋摄入量与结肠癌和直肠癌风险增加有关。
