Pogson D M, Doxey D L, Gilmour J S, Milne E M, Chisholm H K
Department of Veterinary Clinical Studies, Royal (Dick) School of Veterinary Studies, Roslin, Midlothian, U.K.
J Comp Pathol. 1992 Oct;107(3):271-83. doi: 10.1016/0021-9975(92)90003-d.
Histological investigations were undertaken on four sympathetic autonomic ganglia and on the myenteric and sub-mucosal plexuses of the jejunum in healthy animals, in naturally occurring cases of acute, sub-acute and chronic equine dysautonomia and in ponies in which neuronal damage had been induced by the injection of acute grass sickness sera. The degree of neuronal damage is related to the type of dysautonomia. The coeliac-mesenteric ganglion reacts differently from other ganglia and is less severely damaged in cases of short duration. Extensive experimentally induced damage to the coeliac-mesenteric ganglion, even when jejunal damage is also present, is not associated with clinical illness. It is proposed that the rate of autonomic neurone loss and the extent of the damage may both influence the clinical manifestations of grass sickness.
对健康动物的四个交感自主神经节以及空肠的肌间神经丛和黏膜下神经丛进行了组织学研究，研究对象还包括自然发生急性、亚急性和慢性马自主神经功能障碍的病例，以及通过注射急性青草搐搦血清诱导神经元损伤的小马。神经元损伤的程度与自主神经功能障碍的类型有关。腹腔肠系膜神经节的反应与其他神经节不同，在病程较短的病例中损伤较轻。即使存在空肠损伤，对腹腔肠系膜神经节进行广泛的实验性诱导损伤也与临床疾病无关。有人提出，自主神经元丧失的速率和损伤程度可能都会影响青草搐搦的临床表现。
