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在常规临床实践中对糖尿病进行机会性筛查。

Opportunistic screening for diabetes in routine clinical practice.

作者信息

Ealovega Mark W, Tabaei Bahman P, Brandle Michael, Burke Ray, Herman William H

机构信息

Department of Internal Medicine, Division of Endocrinology and Metabolism, University of Michigan Health System, Ann Arbor, Michigan 48109-0354, USA.

出版信息

Diabetes Care. 2004 Jan;27(1):9-12. doi: 10.2337/diacare.27.1.9.

Abstract

OBJECTIVE

Since 1997, the American Diabetes Association has recommended that nondiabetic individuals >/=45 years of age be screened for diabetes at least every 3 years. We sought to characterize the frequency, methods, and results of diabetes screening in routine clinical practice.

RESEARCH DESIGN AND METHODS

We studied opportunistic screening in nondiabetic members of a health maintenance organization >/=45 years of age who were assigned to a large, integrated, academic health care delivery system. Screening was defined as the first glucose, HbA(1c), or oral glucose tolerance test (OGTT) performed between 1 January 1998 and 31 December 2000. Chart review was performed to determine the prevalence of diabetes risk factors and to describe follow-up.

RESULTS

Of 8,286 nondiabetic patients >/=45 years of age, 69% (n = 5,752) were screened. The frequency of screening was greater in patients with one or more primary care visits and increased with age. Women were more likely to be screened than men, and patients with at least one diabetes risk factor were more likely to be screened than those without risk factors. Random plasma glucose was the most common screening test (95%). Four percent (n = 202) of those screened had abnormal results. Only 38% (n = 77) of those with abnormal results received appropriate follow-up, and 17% (n = 35) were diagnosed with diabetes within 6 months of screening. The yield of screening was very low (0.6%, 35 of 5,752).

CONCLUSIONS

Despite frequent screening and appropriate targeting of high-risk patients, follow-up of patients with abnormal results is uncommon and the yield of screening is low. Interventions are needed to help physicians recognize and provide appropriate follow-up for patients with potentially abnormal random glucose levels.

摘要

目的

自1997年以来,美国糖尿病协会建议年龄≥45岁的非糖尿病个体至少每3年筛查一次糖尿病。我们试图描述常规临床实践中糖尿病筛查的频率、方法和结果。

研究设计与方法

我们研究了年龄≥45岁的健康维护组织非糖尿病成员的机会性筛查,这些成员被分配到一个大型的、综合性的学术医疗服务系统。筛查定义为1998年1月1日至2000年12月31日期间进行的首次血糖、糖化血红蛋白(HbA1c)或口服葡萄糖耐量试验(OGTT)。通过查阅病历确定糖尿病危险因素的患病率并描述随访情况。

结果

在8286名年龄≥45岁的非糖尿病患者中,69%(n = 5752)接受了筛查。有一次或多次初级保健就诊的患者筛查频率更高,且随年龄增加而增加。女性比男性更有可能接受筛查,至少有一项糖尿病危险因素的患者比没有危险因素的患者更有可能接受筛查。随机血糖是最常用的筛查试验(95%)。接受筛查的患者中有4%(n = 202)结果异常。结果异常的患者中只有38%(n = 77)得到了适当的随访,17%(n = 35)在筛查后6个月内被诊断为糖尿病。筛查的阳性率非常低(0.6%,5752例中有35例)。

结论

尽管对高危患者进行了频繁筛查且目标明确,但对结果异常患者的随访并不常见,筛查阳性率较低。需要采取干预措施,帮助医生识别随机血糖水平可能异常的患者并提供适当的随访。

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