Sumi Yasunori, Kagami Hideaki, Ohtsuka Yoshiaki, Kakinoki Yasuaki, Haruguchi Yuuji, Miyamoto Hiroshi
Department of Dental Surgery, The National Chubu Hospital-National Institute for Longevity Sciences, Morioka, Obu City, Japan.
Gerodontology. 2003 Dec;20(2):84-7. doi: 10.1111/j.1741-2358.2003.00084.x.
The morbidity and mortality of the dependent elderly that result from aspiration pneumonia are recognized as a major geriatric health problem. Most cases of bacterial pneumonia are initiated following colonization or superinfection of the pharynx by pathogenic bacteria, followed by aspiration of pharyngeal contents. A recent study revealed that bacteria, that commonly cause respiratory infection, colonized the dentures of dependent elderly. This suggests that denture plaque may function as a reservoir of potential respiratory pathogens to facilitate colonization on the pharynx. The purpose of this study was to determine the possible correlation between denture and pharyngeal microflora.
The denture and pharyngeal bacterial flora of 50 dependent elderly were examined, and the microorganisms identified by culturing. The agreement between the bacterial species in denture plaque and pharyngeal microflora was investigated using the Kappa method.
The microorganism species on the dentures and pharyngeal mucosa of the subjects had an agreement rate of 68.5%. The agreement rate for each of the bacterial species of the dentures and pharynx was also demonstrated to be high.
Dentures should be considered an important reservoir of organisations which could colonise the pharynx, and the importance of controlling denture plaque for the prevention of aspiration pneumonia cannot be overemphasized.
因吸入性肺炎导致的失能老年人的发病率和死亡率被认为是一个主要的老年健康问题。大多数细菌性肺炎病例是在病原菌在咽部定植或发生二重感染后，继以吸入咽部内容物而引发的。最近一项研究显示，常见引起呼吸道感染的细菌定植于失能老年人的假牙上。这表明假牙菌斑可能作为潜在呼吸道病原体的储存库，促进在咽部的定植。本研究的目的是确定假牙与咽部微生物群之间可能存在的相关性。
检查了50名失能老年人的假牙和咽部细菌菌群，并通过培养鉴定微生物。使用卡帕方法研究假牙菌斑和咽部微生物群中细菌种类之间的一致性。
受试者假牙和咽部黏膜上的微生物种类一致率为68.5%。假牙和咽部各细菌种类的一致率也很高。
假牙应被视为可能定植于咽部的微生物的重要储存库，对于预防吸入性肺炎而言，控制假牙菌斑的重要性无论如何强调都不为过。
