甲基丙烯酸二甲氨基十六酯和/或2-甲基丙烯酰氧基乙基磷酰胆碱对热聚合和3D打印义齿基托材料弯曲强度及表面硬度的影响

The Effect of Incorporating Dimethylaminohexadecyl Methacrylate and/or 2-Methacryloyloxyethyl Phosphorylcholine on Flexural Strength and Surface Hardness of Heat Polymerized and 3D-Printed Denture Base Materials.

作者信息

AlAzzam Njood F, Bajunaid Salwa O, Mitwalli Heba A, Baras Bashayer H, Weir Michael D, Xu Hockin H K

机构信息

Department of Prosthetic Sciences, College of Dentistry, King Saud University, Riyadh 60169-15, Saudi Arabia.

Department of Restorative Dental Sciences, College of Dentistry, King Saud University, Riyadh 60169-15, Saudi Arabia.

出版信息

Materials (Basel). 2024 Sep 20;17(18):4625. doi: 10.3390/ma17184625.

DOI:10.3390/ma17184625

PMID:39336366

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11433138/

Abstract

BACKGROUND

A major disadvantage of polymethyl methacrylate (PMMA) acrylic resins is susceptibility to biofilm accumulation. The incorporation of antimicrobial agents is a reliable prevention technique. The purpose of this study is to investigate the effect of incorporating dimethylaminohexadecyl methacrylate (DMAHDM) and/or 2-methacryloyloxyethyl phosphorylcholine (MPC) into heat-polymerized (HP) and 3D-printed (3DP) denture base materials on the flexural strength, modulus of elasticity, and surface hardness.

METHODS

DMAHDM and/or MPC were mixed with the acrylic resin liquid of a heat-polymerized (ProBase Hot) and a 3D printed (NextDent Denture 3D) material at mass fractions of 1.5% and 3% and a combination of 3% MPC and 1.5% DMAHDM.

RESULTS

Significant differences in mechanical properties between the control and experimental groups have been detected (-value < 0.0001). In HP materials, the addition of DMAHDM and/or MPC generally decreased the flexural strength, from (151.18 MPa) in G1 down to (62.67 MPa) in G5, and surface hardness, from (18.05 N/mm) down to (10.07 N/mm) in G5. Conversely, in 3DP materials, flexural strength was slightly enhanced, from (58.22 MPa) in G1 up to (62.76 MPa) in G6, although surface hardness was consistently reduced, from (13.57 N/mm) down to (5.29 N/mm) in G5.

CONCLUSION

It is recommended to carefully optimize the concentrations of DMAHDM and/or MPC to maintain mechanical integrity.

摘要

背景

聚甲基丙烯酸甲酯（PMMA）丙烯酸树脂的一个主要缺点是易形成生物膜堆积。加入抗菌剂是一种可靠的预防技术。本研究的目的是探讨将甲基丙烯酸二甲氨基十六酯（DMAHDM）和/或2-甲基丙烯酰氧基乙基磷酰胆碱（MPC）加入热聚合（HP）和3D打印（3DP）义齿基托材料中对弯曲强度、弹性模量和表面硬度的影响。

方法

将DMAHDM和/或MPC与热聚合材料（ProBase Hot）和3D打印材料（NextDent Denture 3D）的丙烯酸树脂液体按质量分数1.5%和3%以及3% MPC与1.5% DMAHDM的组合进行混合。

结果

已检测到对照组和实验组之间机械性能存在显著差异（P值<0.0001）。在HP材料中，加入DMAHDM和/或MPC通常会降低弯曲强度，从G1组的（151.18 MPa）降至G5组的（62.67 MPa），以及表面硬度，从（18.05 N/mm）降至G5组的（10.07 N/mm）。相反，在3DP材料中，弯曲强度略有提高，从G1组的（58.22 MPa）升至G6组的（62.76 MPa），尽管表面硬度持续降低，从（13.57 N/mm）降至G5组的（5.29 N/mm）。