Russo-Mancuso Giovanna, Branciforte Francesca, Licciardello Maria, La Spina Milena
Department of Pediatric Hematology and Oncology, University of Catania, Catania, Italy.
Int J Hematol. 2003 Dec;78(5):429-31. doi: 10.1007/BF02983815.
Recently, an association between Helicobacter pylori (HP) and iron deficiency anemia (IDA) was proposed. We describe 9 pediatric patients with a history of long-standing IDA and HP infection. After HP test results were confirmed to be positive, anti-HP therapy consisting of omeprazole, clarithromycin, and amoxicillin was administered for 2 weeks. The hematologic profile and iron status were assessed before and periodically after the end of the eradication regimen. The eradication of HP was associated with stable normalization of iron stores. HP infection may be involved in cases of IDA of unknown origin, and the eradication of HP is associated with the resolution of anemia.
最近，有人提出幽门螺杆菌（HP）与缺铁性贫血（IDA）之间存在关联。我们描述了9例有长期IDA病史且感染HP的儿科患者。在HP检测结果被确认为阳性后，给予由奥美拉唑、克拉霉素和阿莫西林组成的抗HP治疗2周。在根除方案结束前及结束后定期评估血液学指标和铁状态。HP的根除与铁储备稳定恢复正常有关。HP感染可能与不明原因的IDA病例有关，而HP的根除与贫血的缓解有关。
