Hasselblatt Martin, Sepehrnia Abolghassem, von Falkenhausen Marcus, Paulus Werner
Institute of Neuropathology, University Hospital Münster, Germany.
J Neurosurg. 2003 Dec;99(6):1089-90. doi: 10.3171/jns.2003.99.6.1089.
Intracranial occurrence of follicular dendritic cell (FDC) sarcoma, a rare tumor derived from dendritic cells of the lymphoid follicle, has not yet been described. Therefore, the case of a 53-year-old man presenting with an intracranial mass invading the clivus is reported. The diagnosis of FDC sarcoma was confirmed by immunohistochemical staining for dendritic cell markers, that is, CD21, CD23, and CD35. Due to some similarities with meningioma, intracranial FDC sarcoma might be an underdiagnosed disease.
颅内滤泡树突状细胞(FDC)肉瘤是一种源自淋巴滤泡树突状细胞的罕见肿瘤,其颅内发生情况尚未见报道。因此,本文报告了一例53岁男性患者,其颅内肿块侵犯斜坡。通过对树突状细胞标志物即CD21、CD23和CD35进行免疫组化染色,确诊为FDC肉瘤。由于与脑膜瘤存在一些相似之处,颅内FDC肉瘤可能是一种诊断不足的疾病。