Toyoda K, Taniguchi J, Kikawa K, Uike N, Haraoka S, Ooshima K, Kikuchi M, Kawanishi H
Department of Internal Medicine, Fukuoka Tokusyuukai Hospital.
Intern Med. 2000 Nov;39(11):950-5. doi: 10.2169/internalmedicine.39.950.
A rare case of follicular dendritic cell (FDC) sarcoma is reported. A 71-year-old woman was admitted for evaluation of constipation. Computerized tomography showed cervical, supraclavicular, retroperitoneal, and paraaortic lymphadenopathies. Histological findings from a cervical lymph node revealed Hodgkin's disease at first. But tumors that arose both in the cervical and the left interscapular regions during the chemotherapy were immunohistochemically confirmed to be of follicular dendritic cell origin. The ultrastructural findings were consistent with those of FDC sarcoma. FDC sarcoma is a rare nonlymphoid cell-derived malignant tumor originating from the lymphoid tissue. The diagnosis of FDC sarcoma is most accurately established by immunohistochemical methods, using its specific markers.
报告了一例罕见的滤泡树突状细胞（FDC）肉瘤病例。一名71岁女性因便秘入院评估。计算机断层扫描显示颈部、锁骨上、腹膜后和主动脉旁淋巴结肿大。最初，颈部淋巴结的组织学检查结果显示为霍奇金病。但化疗期间颈部和左肩胛间区域出现的肿瘤经免疫组织化学证实为滤泡树突状细胞起源。超微结构检查结果与FDC肉瘤相符。FDC肉瘤是一种罕见的非淋巴细胞源性恶性肿瘤，起源于淋巴组织。FDC肉瘤的诊断最准确地通过使用其特异性标志物的免疫组织化学方法来确立。
