Carme B, Yombi B, Bouquety J C, Plassard H, Nzingoula S, Senga J, Akani I
Faculté de Médecine et CHRU d'Amiens, Hôpital Sud, France.
Trop Med Parasitol. 1992 Sep;43(3):173-6.
This study was conducted in all four hospitals of Brazzaville, the capital of the Congo in order to assess the trend in malaria morbidity, the frequency of cerebral malaria and the related mortality between 1983 and 1989 in Brazzaville children. For the period 1983 to 1987 the study was retrospective, based on records. For the period 1988 and 1989 a prospective study was carried out in the two main hospitals in which a system for reporting cases of cerebral malaria was set up. This was completed by a retrospective analysis of data similar to that carried for the previous years. The population of Brazzaville children aged between 0 and 14 years and the distribution by district were estimated from the 1984 official census taking the annual demographic growth to be 5%. The results show a marked increase in hospitalizations for malaria, noticeable since 1985, and which now account for about 50% of the overall non-surgical hospitalizations. The number of cases of cerebral malaria and related deaths have probably increased. However, these severe forms of malaria were relatively rare. Indeed, in 1988 and 1989, for the 0-4, 5-9 and 10-14 year age groups, the annual incidence rates of cerebral malaria were estimated at respectively 240, 61 and 13 per 100,000 and the related mortality rates at respectively 58, 5 and 1 per 100,000. No obvious relationship was found between the intensity of malaria transmission, which varied considerably according to the district, and the level of mortality from cerebral malaria.
本研究在刚果首都布拉柴维尔的所有四家医院开展，旨在评估1983年至1989年期间布拉柴维尔儿童疟疾发病率趋势、脑型疟发病频率及相关死亡率。1983年至1987年期间，该研究为基于记录的回顾性研究。1988年和1989年，在两家主要医院开展了前瞻性研究，建立了脑型疟病例报告系统，并通过对与前几年类似数据的回顾性分析加以完善。根据1984年官方人口普查数据，以每年5%的人口增长率估算了布拉柴维尔0至14岁儿童的人口数量及按地区的分布情况。结果显示，自1985年以来，疟疾住院人数显著增加，目前约占非手术住院总数的50%。脑型疟病例数及相关死亡人数可能有所增加。然而，这些严重疟疾病例相对较少。事实上，在1988年和1989年，0至4岁、5至9岁和10至14岁年龄组的脑型疟年发病率分别估计为每10万人240例、61例和13例，相关死亡率分别为每10万人58例、5例和1例。研究发现，疟疾传播强度因地区而异，且与脑型疟死亡率之间没有明显关联。
