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与下午接受腺样体扁桃体切除术的重度阻塞性睡眠呼吸暂停患儿相比,上午接受该手术的患儿术后发生血氧饱和度下降的可能性更低。

Children with severe OSAS who have adenotonsillectomy in the morning are less likely to have postoperative desaturation than those operated in the afternoon.

作者信息

Koomson Albert, Morin Isabelle, Brouillette Robert, Brown Karen A

机构信息

Department of Anesthesia, Montreal Children's Hospital, Montreal, Quebec, Canada.

出版信息

Can J Anaesth. 2004 Jan;51(1):62-7. doi: 10.1007/BF03018549.

Abstract

PURPOSE

To determine, in a subset of children previously reported, if the time of day when adenotonsillectomy for severe obstructive sleep apnea syndrome (OSAS) was performed affected the incidence of postoperative respiratory complications.

CLINICAL FEATURES

Children having adenotonsillectomy were included if they had a polysomnographic diagnosis of severe OSAS within six months prior to operation. Patients who met the inclusion criteria were grouped by the occurrence of postoperative desaturation into a saturated (SAT) and desaturated (deSAT) group. The charts of children in group deSAT were reviewed. The clock time of the surgical procedure was recorded and categorized as morning (AM) or afternoon (PM).

RESULTS

Eighty-eight patients met the inclusion criteria. There were 31 girls and 57 boys. The mean +/- SD age (yr) and weight (kg) were 4.6 +/- 2.9 yr and 20.8 +/- 14.5 kg respectively. There were 63 children in the SAT group and 25 in the deSAT group. Differences in age, weight and gender were not significant. The preoperative oxygen saturation (SaO2) nadir for the SAT and deSAT groups was 80.8 +/- 10.2% and 67.6 +/- 17.5% (P < 0.05) respectively. The preoperative obstructive apnea and hypopnea index was 15.8 +/- 10.2 and 35.7 +/- 34.6 events.hr(-1) (P < 0.05), respectively. Surgery in 63 (71.6%) children was performed in the AM. Univariate logistic regression identified PM surgery [odds ratio (OR) 4.6, 95% confidence interval (CI) 1.7 to 12.6, P = 0.002] and a preoperative SaO2 nadir < 80% (OR 3.6, 95% CI 1.4 to 9.4, P = 0.009) as risk factors predicting postadenotonsillectomy desaturation.

CONCLUSION

Children with severe OSAS whose surgery is performed in the AM are less likely to desaturate following adenotonsillectomy than children whose surgery is performed in the PM.

摘要

目的

在先前报道的一组儿童中,确定重度阻塞性睡眠呼吸暂停综合征(OSAS)行腺样体扁桃体切除术的时间是否会影响术后呼吸并发症的发生率。

临床特征

如果儿童在手术前6个月内通过多导睡眠图诊断为重度OSAS,则纳入行腺样体扁桃体切除术的儿童。符合纳入标准的患者根据术后低氧饱和度的发生情况分为饱和组(SAT)和低氧饱和组(deSAT)。对deSAT组儿童的病历进行回顾。记录手术的时钟时间,并分为上午(AM)或下午(PM)。

结果

88例患者符合纳入标准。其中女孩31例,男孩57例。平均±标准差年龄(岁)和体重(千克)分别为4.6±2.9岁和20.8±14.5千克。SAT组有63名儿童,deSAT组有25名。年龄、体重和性别差异无统计学意义。SAT组和deSAT组术前最低氧饱和度(SaO2)分别为80.8±10.2%和67.6±17.5%(P<0.05)。术前阻塞性呼吸暂停和低通气指数分别为15.8±10.2和35.7±34.6次/小时(P<0.05)。63例(71.6%)儿童在上午进行手术。单因素逻辑回归分析确定下午手术[比值比(OR)4.6,95%置信区间(CI)1.7至12.6,P = 0.002]和术前最低SaO2<80%(OR 3.6,95%CI 1.4至9.4,P = 0.009)是预测腺样体扁桃体切除术后低氧饱和度的危险因素。

结论

与下午进行手术的儿童相比,上午进行重度OSAS手术的儿童在腺样体扁桃体切除术后发生低氧饱和度的可能性较小。

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