Chishti Aftab S
Department of Pediatrics, King Faisal University, PO Box 40241, Al-Khobar, Kingdom of Saudi Arabia.
Saudi Med J. 2003 Dec;24(12):1292-5.
Hypertension is one of the major contributors to cardiovascular, renal and central nervous system morbidity and mortality. Although it is more prevalent in the adult population, hypertension and its sequelae are being seen in the pediatric population with increasing frequency. Blood pressure (BP) is not a static phenomenon. It is highly variable, changing constantly in response to various activities, stimuli, and stresses. Consideration of all of these factors make intermittent clinic BP measurements less effective in accounting for BP rhythmicity so ambulatory BP monitoring has emerged as a useful tool to give a detailed analysis of BP patterns during the day and night. It is becoming more and more evident that ABPM could be a useful tool in evaluation of white coat hypertension, apparent drug resistant hypertension, to evaluate efficacy of medications for control of hypertension, in evaluation of borderline hypertension, to further elaborate on chronology of hypertension and above all to assess the end organ damage risk as measurement of 24 hour BP parameters do correlate with hypertensive end organ injury.
高血压是导致心血管、肾脏和中枢神经系统发病和死亡的主要因素之一。尽管高血压在成年人群中更为普遍,但在儿科人群中,高血压及其后遗症的出现频率也在不断增加。血压(BP)并非静态现象。它具有高度变异性,会因各种活动、刺激和压力而不断变化。考虑到所有这些因素,间歇性诊室血压测量在解释血压节律性方面效果较差,因此动态血压监测已成为一种有用的工具,可对白天和夜间的血压模式进行详细分析。越来越明显的是,动态血压监测在评估白大衣高血压、疑似顽固性高血压、评估控制高血压药物的疗效、评估临界高血压、进一步阐述高血压的病程,以及最重要的是评估终末器官损伤风险方面可能是一种有用的工具,因为24小时血压参数的测量与高血压性终末器官损伤确实相关。