Ansari Naseem A, Al-Ratrout Jihad T
Department of Pathology, College of Medicine & Medical Sciences, Arabian Gulf University, Bahrain.
Saudi Med J. 2003 Dec;24(12):1296-9.
Histiocytic proliferations may be reactive or neoplastic. The neoplastic proliferations (histiocytoses) are subdivided into a few categories. One of these categories is the non-Langerhan's cell histiocytoses (NLCH). Cutaneous NLCH is a heterogeneous collection of conditions which can be sub grouped on the basis of the morphological appearance of the lesional histiocyte into xanthomatized, oncocytic, vacuolated, spindle-cell and polymorphous subtypes. The clinical characteristics and histological appearances of a variety of conditions within each subtype are discussed.
组织细胞增殖可能是反应性的或肿瘤性的。肿瘤性增殖(组织细胞增多症)可细分为几类。其中一类是非朗格汉斯细胞组织细胞增多症(NLCH)。皮肤NLCH是一组异质性疾病,可根据病变组织细胞的形态外观分为黄瘤样、嗜酸性、空泡状、梭形细胞和多形性亚型。本文讨论了各亚型中多种疾病的临床特征和组织学表现。