Todd Neil P McAngus, Rosengren Sally M, Colebatch James G
Department of Psychology, University of Manchester, Manchester M13 9PL, United Kingdom.
J Acoust Soc Am. 2003 Dec;114(6 Pt 1):3264-72. doi: 10.1121/1.1628249.
In this paper data are presented from an experiment which provides evidence for the existence of a short latency, acoustically evoked potential of probable vestibular origin. The experiment was conducted in two phases using bone-conducted acoustic stimulation. In the first phase subjects were stimulated with 6-ms, 500-Hz tone bursts in order to obtain the threshold V(T) for vestibular evoked myogenic potentials (VEMP). It was confirmed that the difference between bone-conducted auditory and acoustic vestibular thresholds was slightly over 30 dB. The estimated threshold was then used as a reference value in the second part of the experiment to stimulate subjects over a range of intensities from -6 to +18 dB (re: V(T)). Averaged EEG recordings were made with eight Ag/AgCl electrodes placed on the scalp at Fpz, F3, F4, F7, F8, Cz, T3, and T4 according to the 10-20 system. Below V(T) auditory midlatency responses (MLRs) were observed. Above V(T) two additional potentials appeared: a positivity at about 10 ms (P10) which was maximal at Cz, and a negativity at about 15 ms (N15) which was maximal at Fpz. Extrapolation of the growth functions for the P10 and N15 indicated a threshold close to V(T), consistent with a vestibular origin of these potentials. Given the low threshold of vestibular acoustic sensitivity it is possible that this mode may make a contribution to the detection of and affective responses to loud low frequency sounds. The evoked potentials may also have application as a noninvasive and nontraumatic test of vestibular projections to the cortex.
本文展示了一项实验的数据，该实验为可能起源于前庭的短潜伏期听觉诱发电位的存在提供了证据。实验分两个阶段进行，采用骨传导声刺激。在第一阶段，用6毫秒、500赫兹的短音脉冲刺激受试者，以获得前庭诱发肌源性电位（VEMP）的阈值V(T)。结果证实，骨传导听觉阈值与前庭听觉阈值之差略超过30分贝。然后，在实验的第二部分，将估计的阈值用作参考值，在-6至+18分贝（相对于V(T)）的强度范围内刺激受试者。根据10-20系统，在头皮的Fpz、F3、F4、F7、F8、Cz、T3和T4处放置八个Ag/AgCl电极，进行脑电图平均记录。在V(T)以下观察到听觉中潜伏期反应（MLR）。在V(T)以上出现了另外两种电位：约10毫秒时的正电位（P10），在Cz处最大；约15毫秒时的负电位（N15），在Fpz处最大。P10和N15增长函数的外推表明阈值接近V(T)，这与这些电位起源于前庭一致。鉴于前庭听觉敏感性阈值较低，这种模式可能有助于检测低频强声并产生情感反应。诱发电位也可作为一种对前庭向皮层投射的非侵入性和非创伤性测试。
