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青少年及成年期自闭症谱系障碍的症状。

The symptoms of autism spectrum disorders in adolescence and adulthood.

作者信息

Seltzer Marsha Mailick, Krauss Marty Wyngaarden, Shattuck Paul T, Orsmond Gael, Swe April, Lord Catherine

机构信息

Waisman Center, University of Wisconsin-Madison, Madison, Wisconsin 53705-2280, USA.

出版信息

J Autism Dev Disord. 2003 Dec;33(6):565-81. doi: 10.1023/b:jadd.0000005995.02453.0b.

Abstract

This article describes the symptoms of autism spectrum disorders (ASD) manifested by 405 individuals between the ages of 10 and 53 years, all of whom had an ASD diagnosis. Data were collected using the Autism Diagnostic Interview-Revised (ADI-R) to assess the pattern of autism symptoms in adolescence and adulthood. Findings include that although virtually all sample members met the criteria for Autistic Disorder earlier in their childhood, just over half (54.8%) would have met autism criteria if current scores were used to complete the diagnostic algorithm; that adolescents were more likely to improve in the Reciprocal Social Interaction domain than the adults, whereas the adults were more likely to improve in the Restricted, Repetitive Behaviors and Interests domain, and there were no differences in severity of symptoms between cohorts in the Communication domain; and that individual symptoms showed unique trajectories, with greatest symptom abatement between lifetime and current ADI-R ratings for speaking in at least three-word phrases and the least symptom improvement for having friendships. Findings were interpreted in the context of life course development, reformulations of diagnostic criteria, and changing service contexts for individuals with autism spectrum disorders.

摘要

本文描述了405名年龄在10至53岁之间的自闭症谱系障碍(ASD)患者所表现出的症状,他们均被诊断患有ASD。使用修订版自闭症诊断访谈量表(ADI-R)收集数据,以评估青少年期和成年期的自闭症症状模式。研究结果包括:尽管几乎所有样本成员在童年早期都符合自闭症障碍的标准,但如果使用当前分数来完成诊断算法,仅有略超过一半(54.8%)的人符合自闭症标准;青少年在相互社交互动领域比成年人更有可能改善,而成年人在局限的、重复的行为和兴趣领域更有可能改善,并且在沟通领域不同队列之间的症状严重程度没有差异;个体症状呈现出独特的轨迹,在使用至少三个单词的短语说话方面,从终生ADI-R评分到当前ADI-R评分症状减轻最多,而在拥有友谊方面症状改善最少。研究结果是在生命历程发展、诊断标准的重新制定以及自闭症谱系障碍患者服务环境变化的背景下进行解释的。

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