Petri András, Höhn József, Wolfárd Antal, László Kókai Erzsébet, Kocsis Savanya Gábor, Boros Mihály, Balogh Adám
Sebészeti Klinika, Szegedi Egyetem, Altalános Orvostudományi Kar, Szeged 6720, Hungary.
Magy Onkol. 2003;47(4):391-5. Epub 2004 Jan 11.
Our aim is to give an audit of our experience over the past two decades in the form of a retrospective study.
PATIENTS/METHODS: Between 1 January, 1982 and 15 December, 2001, 133 patients with benign liver tumor (adenoma: 22, focal nodular hyperplasia: 27, hemangioma: 83, lipoma: 1) were treated. A total of 113 patients underwent surgery, while 20 asymptomatic cases were merely observed. The mean age, the female/male ratio and the size of the tumor in the adenoma cases were 38.3+/-10.2 years, 20/2 and 7.7+/-2.4 cm, while for focal nodular hyperplasia they were 39.5+/-12.4, 24/3 and 6.3+/-2.7 cm, and for hemangioma 49.01+/-10.7, 62/21 and 6.5+/-3.6 cm. The results were compared and analyzed statistically.
Enucleation was performed in 53.1% of the patients, non-anatomical resection in 24.8%, segmentectomy in 6.2%, lobectomy in 4.4%, extended lobectomy in 1.8%, stitching in 5.3%, exploration in 3.5% and liver transplantation in 0.9%. The overall 30-day postoperative mortality was 0.9% (1/113). Minor or major complications occurred in a total of 27.4%.
Patients with asymptomatic focal nodular hyperplasia or hemangiomas must be excluded from surgery. Surgery is indicated only when growth or severe complaints are observed. Adenomas must be resected because of the precancerous behavior and the danger of bleeding from a rupture.
我们的目的是通过一项回顾性研究,对过去二十年的经验进行一次审核。
患者/方法:在1982年1月1日至2001年12月15日期间,对133例良性肝肿瘤患者(腺瘤:22例,局灶性结节性增生:27例,血管瘤:83例,脂肪瘤:1例)进行了治疗。共有113例患者接受了手术,而20例无症状患者仅进行了观察。腺瘤病例的平均年龄、男女比例和肿瘤大小分别为38.3±10.2岁、20/2和7.7±2.4厘米,局灶性结节性增生患者分别为39.5±12.4岁、24/3和6.3±2.7厘米,血管瘤患者分别为49.01±10.7岁、62/21和6.5±3.6厘米。对结果进行了统计学比较和分析。
53.1%的患者进行了摘除术,24.8%进行了非解剖性切除术,6.2%进行了段切除术,4.4%进行了叶切除术,1.8%进行了扩大叶切除术,5.3%进行了缝合术,3.5%进行了探查术,0.9%进行了肝移植术。术后30天的总体死亡率为0.9%(1/113)。总共27.4%的患者出现了轻微或严重并发症。
无症状的局灶性结节性增生或血管瘤患者必须排除在手术之外。仅在观察到生长或出现严重症状时才考虑手术。由于腺瘤具有癌前行为和破裂出血的危险,必须进行切除。