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[22例肝脏良性肿瘤切除手术的结果]

[Results of the excision of benign tumors of the liver in 22 patients].

作者信息

Vons C, Smadja C, Kemeny F, Lejeune R, Grange D, Franco D

机构信息

Groupe de Recherche sur la Chirurgie du Foie et de l'Hypertension Portale, Université Paris XI.

出版信息

Gastroenterol Clin Biol. 1989 Mar;13(3):280-4.

PMID:2731679
Abstract

Between 1979 and 1987, 22 patients underwent resection for a benign liver tumor. A total of 24 tumors were resected: 8 adenomas, 8 focal nodular hyperplasias and 8 hemangiomas. In two patients, focal nodular hyperplasia was associated with hemangioma. Preoperative diagnosis of the nature of the tumor by radiologic investigations (ultrasonography, CT-scan, and selective angiography) was made in only 4 patients (18 p. 100), 3 with hemangioma and one with focal nodular hyperplasia. Ten patients underwent major hepatectomies and 12 had either a segmentectomy (8 patients) or atypical resection (4 patients). Progress in operative management significantly decreased transfusion of packed red cells (p less than 0.05) and that of fresh frozen plasma (p less than 0.02). Ten patients received no blood for fresh frozen plasma. Suppression of abdominal drainage when surgery was uneventful significantly decreased postoperative in-hospital stay (p less than 0.05) to a low 7.8 +/- 0.8 days and improved comfort of patients. These results confirm that preoperative diagnosis of a benign liver tumor is uneasy. They suggest that resection has become a benign procedure in selected surgical centers. The risk of ignoring malignant tumors or leaving a tumor with potential complications should prompt resection when the nature of a liver tumor has not been precisely determined by usual radiologic investigative procedures.

摘要

1979年至1987年间,22例患者因良性肝肿瘤接受了切除术。共切除24个肿瘤:8个腺瘤、8个局灶性结节性增生和8个血管瘤。2例患者的局灶性结节性增生与血管瘤相关。仅4例患者(占18%)通过放射学检查(超声、CT扫描和选择性血管造影)在术前诊断出肿瘤性质,其中3例为血管瘤,1例为局灶性结节性增生。10例患者接受了肝大部切除术,12例患者进行了肝段切除术(8例)或非典型切除术(4例)。手术管理的进步显著减少了浓缩红细胞的输注量(p<0.05)和新鲜冰冻血浆的输注量(p<0.02)。10例患者未输注新鲜冰冻血浆。手术顺利时不放置腹腔引流显著缩短了术后住院时间(p<0.05),降至7.8±0.8天的低水平,并提高了患者的舒适度。这些结果证实,术前诊断良性肝肿瘤并不容易。它们表明,在选定的外科中心,切除术已成为一种安全的手术。当肝脏肿瘤的性质未通过常规放射学检查程序精确确定时,忽视恶性肿瘤或留下有潜在并发症的肿瘤的风险应促使进行切除术。

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