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高强度电脉冲抑制肉瘤以提高抗肿瘤药物疗效的研究

[Study of high-intensity electric pulse inhibited sarcoma for improving antitumor drug effect].

作者信息

Li Hong, Wang Zishu, Yue Bisong, Zou Fangdong, Yang Kong, Sun Jingru, Wang Baoyi, Zhang Hong, Chen Haichuan, Yang Guo

机构信息

College of Life Science, Sichuan University, Chengdu 610064.

出版信息

Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2003 Dec;20(4):612-4.

PMID:14716858
Abstract

This article reports the experiment studies on treating the S-180 sarcomas of KM mice with high-intensity electric pulse and antitumor drug (cyclophosphamide). The results showed that the experimental group of electric field combined with drug has the best effect on tumor, compared with the control group. In addition, electric field can inhibit the formation of vas Capillaries and decrease the supply of nutrition for tumor cell. In conclusion, electric field has inhibited the growth of tumor.

摘要

本文报道了用高强度电脉冲联合抗肿瘤药物(环磷酰胺)治疗KM小鼠S-180肉瘤的实验研究。结果表明,与对照组相比,电场联合药物实验组对肿瘤的治疗效果最佳。此外,电场可抑制毛细血管的形成,减少肿瘤细胞的营养供应。总之,电场抑制了肿瘤的生长。

相似文献

1
[Study of high-intensity electric pulse inhibited sarcoma for improving antitumor drug effect].高强度电脉冲抑制肉瘤以提高抗肿瘤药物疗效的研究
Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2003 Dec;20(4):612-4.
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[Inhibitory effect of electrochemotherapy on S180 tumor growth and angiogenesis and the possible mechanism].
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