Kyle J, Ewen S W
Department of Surgery, University of Aberdeen.
Ann R Coll Surg Engl. 1992 Nov;74(6):387-90.
Fourteen examples of carcinoma developing in the colon or rectum were encountered in a series of 1008 patients with Crohn's disease treated in Aberdeen during the 34-year period, 1955-1988. Seven patients were under 55 years of age at the time of onset of Crohn's disease, and had a long history of the disease before carcinoma supervened. Older patients had short histories and a better prognosis. One squamous carcinoma may have arisen in relationship to a fistula in ano.
在1955年至1988年的34年间，阿伯丁对1008例克罗恩病患者进行了治疗，其中有14例在结肠或直肠发生了癌变。7例患者在克罗恩病发病时年龄在55岁以下，在癌变发生之前该疾病已有很长的病史。年龄较大的患者病史较短，预后较好。1例鳞状细胞癌可能与肛瘘有关。
