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银屑病关节炎平片影像学特征的操作定义及观察者可靠性

Operational definitions and observer reliability of the plain radiographic features of psoriatic arthritis.

作者信息

Taylor William J, Porter Guy G, Helliwell Philip S

机构信息

Rheumatology and Rehabilitation Research Unit, University of Leeds, Leeds, United Kingdom.

出版信息

J Rheumatol. 2003 Dec;30(12):2645-58.

Abstract

OBJECTIVE

To determine the standardization and the observer reliability of potentially diagnostic plain radiographic features of psoriatic arthritis (PsA).

METHODS

Radiographic features were chosen on the basis of a systematic review of the literature. One hundred sixty-four radiographs from 62 patients were selected from various sources by a musculoskeletal radiologist. Radiographs were read independently by 2 observers (WJT, PSH) and scored for the presence or absence of each evaluated feature. Cohen's kappa was used to determine observer agreement beyond chance, and the accuracy of each observer (with reference to the radiologist's judgment) was determined by likelihood ratios.

RESULTS

The 2 observers demonstrated similar accuracy, although WJT tended to be more accurate for items classed as absent and PSH more accurate for items classed as present. The following features showed sufficient reliability to be reasonably included in further testing of their discriminatory value (intra- and interobserver kappa values): marginal syndesmophyte (0.68, 0.69), non-marginal syndesmophyte (0.75, 0.59), paravertebral ossification (0.89, 0.79), destructive discovertebral lesion (0.85, 0.65), Romanus lesion (0.64, 0.43), sacroiliitis (0.99, 0.86), entheseal erosion (0.80, 0.71), entheseal ossification (0.69, 0.76), distal interphalangeal erosive disease (0.58, 0.52), joint osteolysis (0.62, 0.47), juxtaarticular bony proliferation (0.43, 0.42), bony ankylosis (0.53, 0.54), tuft osteolysis (0.51, 0.36). The features that showed inadequate reliability were: loss of cortical definition of terminal tuft (0.33, 0.31) and periosteal new bone formation (0.42, 0.03).

CONCLUSION

A number of plain radiographic features of PsA have sufficient reliability to justify inclusion in diagnostic classification criteria sets for further testing.

摘要

目的

确定银屑病关节炎(PsA)潜在诊断性X线平片特征的标准化及观察者可靠性。

方法

基于对文献的系统回顾选择X线特征。一名肌肉骨骼放射科医生从不同来源选取了62例患者的164张X线片。由2名观察者(WJT、PSH)独立阅片,并对每个评估特征的存在与否进行评分。采用Cohen's kappa系数确定观察者间超出偶然因素的一致性,每个观察者的准确性(参考放射科医生的判断)通过似然比来确定。

结果

2名观察者表现出相似的准确性,尽管WJT对分类为不存在的项目往往更准确,而PSH对分类为存在的项目更准确。以下特征显示出足够的可靠性,可合理纳入其鉴别价值的进一步测试中(观察者内和观察者间kappa值):边缘性骨桥(0.68,0.69)、非边缘性骨桥(0.75,0.59)、椎旁骨化(0.89,0.79)、破坏性椎体病变(0.85,0.65)、Romanus病变(0.64,0.43)、骶髂关节炎(0.99,0.86)、附着点侵蚀(0.80,0.71)、附着点骨化(0.69,0.76)、远端指间侵蚀性疾病(0.58,0.52)、关节骨质溶解(0.62,0.47)、关节周围骨质增生(0.43,0.42)、骨融合(0.53,0.54)、指骨末端骨质溶解(0.51,0.36)。可靠性不足的特征为:指骨末端皮质轮廓消失(0.33,0.31)和骨膜新生骨形成(0.42,0.03)。

结论

PsA的一些X线平片特征具有足够的可靠性,足以纳入诊断分类标准集进行进一步测试。

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