Pappas G, Liberopoulos E, Tsianos E, Elisaf M
Department of Internal Medicine, University Hospital of Ioannina, GR 451 10 Ioannina, Greece.
J Infect. 2004 Feb;48(2):206-8. doi: 10.1016/j.jinf.2003.08.001.
Motile Enterococci are rare causes of enterococcal bacteremia, usually in immunocompromised patients. We describe a case of polymicrobial bacteremia, including Enterococcus casseliflavus, Escherichia coli, and Morganella morganii, in an 80-year old woman, shortly after a liver biopsy performed to exclude cholangiocarcinoma. We further discuss the unique genetic characteristics and the clinical significance of such isolates, such as their intrinsic resistance to vancomycin, and the low virulence exhibited clinically. Further workup on the mechanisms of motile Enterococci resistance to vancomycin could probably yield useful information in achieving new ways of facing resistance attributed to the more usual, and malignant Enterococci.
运动性肠球菌是肠球菌菌血症的罕见病因，通常发生在免疫功能低下的患者中。我们描述了一例80岁女性在进行肝活检以排除胆管癌后不久发生的多微生物菌血症病例，其中包括格氏肠球菌、大肠埃希菌和摩根摩根菌。我们进一步讨论了这些分离株的独特遗传特征及其临床意义，例如它们对万古霉素的固有耐药性以及临床上表现出的低毒力。对运动性肠球菌对万古霉素耐药机制的进一步研究可能会为应对更常见且具有致病性的肠球菌所导致的耐药性提供新方法提供有用信息。
