Reznick A Z, Witt E, Matsumoto M, Packer L
Department of Morphological Sciences, Technion Faculty of Medicine, Haifa, Israel.
Biochem Biophys Res Commun. 1992 Dec 15;189(2):801-6. doi: 10.1016/0006-291x(92)92273-z.
It is well known that exercise induces lipid peroxidation in skeletal muscle and that vitamin E prevents exercise-induced lipid damage. In this study we show for the first time, an increase in protein oxidation in skeletal muscle after a single bout of exercise, related to an exercise-induced decrease in lipophilic antioxidants, and substantial protection against both resting and exercise-induced protein oxidation by supplementation with various isomers (alpha-tocopherol, alpha-tocotrienol) of vitamin E.
众所周知，运动可诱导骨骼肌中的脂质过氧化，而维生素E可预防运动诱导的脂质损伤。在本研究中，我们首次表明，单次运动后骨骼肌中的蛋白质氧化增加，这与运动诱导的亲脂性抗氧化剂减少有关，并且补充维生素E的各种异构体（α-生育酚、α-生育三烯酚）可对静息和运动诱导的蛋白质氧化提供实质性保护。
