Davidson J
Department of Psychiatry, Duke University Medical Center, Durham, North Carolina 27710.
Br J Psychiatry. 1992 Mar;160:309-14. doi: 10.1192/bjp.160.3.309.
Post-traumatic stress disorder (PTSD) is a recently introduced diagnosis. The disorder is quite common, yet often unrecognised, and leads to significant morbidity or mortality. Effective treatment often entails use of psychotropic medication. Only recently has this become apparent, and awareness of the role of drug therapy in PTSD remains limited. A number of studies have indicated efficacy for antidepressant, mood-stabilising, anticonvulsant and antianxiety medications. This review describes the role of pharmacotherapy, by examining issues of diagnosis and recognition of PTSD, the theoretical basis for drug use, goals of drug treatment, dose ranges, and clinical application of psychotropic drugs.
创伤后应激障碍（PTSD）是一种最近才引入的诊断。这种疾病相当常见，但往往未被识别，会导致严重的发病或死亡。有效的治疗通常需要使用精神药物。直到最近这一点才变得明显，而且对药物治疗在创伤后应激障碍中作用的认识仍然有限。一些研究表明抗抑郁药、心境稳定剂、抗惊厥药和抗焦虑药有疗效。这篇综述通过研究创伤后应激障碍的诊断和识别问题、药物使用的理论基础、药物治疗目标、剂量范围以及精神药物的临床应用，描述了药物治疗的作用。
