Yang Yun-Liang
Department of Biological Science and Technology, National Chiao Tung University, Hsinchu, Taiwan, ROC.
J Microbiol Immunol Infect. 2003 Dec;36(4):223-8.
Candida albicans is an opportunistic human pathogen, which colonizes at several anatomically distinct sites including skin, oral, gastrointestinal tract, and vagina. How harmless commensal C. albicans become a human pathogen when opportunity comes is not clear. This review will focus on the molecular dissection of virulence factors of C. albicans, including adhesion, proteinases secretion, hyphal formation, and phenotypic switching. This review will also describe briefly the virulence factors in non-albicans Candida spp.
白色念珠菌是一种机会性人类病原体，它定殖于几个解剖学上不同的部位，包括皮肤、口腔、胃肠道和阴道。尚不清楚无害的共生白色念珠菌在时机来临时如何变成人类病原体。本综述将聚焦于白色念珠菌毒力因子的分子剖析，包括黏附、蛋白酶分泌、菌丝形成和表型转换。本综述还将简要描述非白色念珠菌属念珠菌的毒力因子。
