免疫复合物介导的疾病
Immune complex mediated diseases.
作者信息
McCluskey R T, Hall C L, Colvin R B
出版信息
Hum Pathol. 1978 Jan;9(1):71-84. doi: 10.1016/s0046-8177(78)80009-4.
Immune complexes formed in the circulation are believed to be the principal pathogenetic agents in certain human diseases, notably in various forms of glomerulonephritis and arteritis. Criteria for the recognition of immune complex deposits in tissue are discussed and recently developed sensitive methods that detect circulating immune complexes are reviewed. In addition, the evidence implicating certain antigens and causative agents in human immune complex mediated glomerulonephritis and arteritis is evaluated.
循环系统中形成的免疫复合物被认为是某些人类疾病，尤其是各种形式的肾小球肾炎和动脉炎的主要致病因子。本文讨论了识别组织中免疫复合物沉积的标准，并综述了最近开发的检测循环免疫复合物的敏感方法。此外，还评估了在人类免疫复合物介导的肾小球肾炎和动脉炎中涉及某些抗原和病原体的证据。
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