Wheeler Anthony H
Pain and Orthopedic Neurology, Charlotte Spine Center, Charlotte, North Carolina 28207, USA.
Drugs. 2004;64(1):45-62. doi: 10.2165/00003495-200464010-00004.
Voluntary muscle is the largest human organ system. The musculotendinous contractual unit sustains posture against gravity and actuates movement against inertia. Muscular injury can occur when soft tissues are exposed to single or recurrent episodes of biomechanical overloading. Muscular pain is often attributed to a myofascial pain disorder, a condition originally described by Drs Janet Travell and David Simons. Among patients seeking treatment from a variety of medical specialists, myofascial pain has been reported to vary from 30% to 93% depending on the subspecialty practice and setting. Forty-four million Americans are estimated to have myofascial pain; however, controversy exists between medical specialists regarding the diagnostic criteria for myofascial pain disorders and their existence as a pathological entity. Muscles with activity or injury-related pain are usually abnormally shortened with increased tone and tension. In addition, myofascial pain disorders are characterised by the presence of tender, firm nodules called trigger points. Within each trigger point is a hyperirritable spot, the 'taut-band', which is composed of hypercontracted extrafusal muscle fibres. Palpation of this spot within the trigger point provokes radiating, aching-type pain into localised reference zones. Research suggests that myofascial pain and dysfunction with characteristic trigger points and taut-bands are a spinal reflex disorder caused by a reverberating circuit of sustained neural activity in a specific spinal cord segment. The treatment of myofascial pain disorders requires that symptomatic trigger points and muscles are identified as primary or ancillary pain generators. Mechanical, thermal and chemical treatments, which neurophysiologically or physically denervate the neural loop of the trigger point, can result in reduced pain and temporary resolution of muscular overcontraction. Most experts believe that appropriate treatment should be directed at the trigger point to restore normal muscle length and proper biomechanical orientation of myofascial elements, followed by treatment that includes strengthening and stretching of the affected muscle. Chronic myofascial pain is usually a product of both physical and psychosocial influences that complicate convalescence.
随意肌是人体最大的器官系统。肌肉 - 肌腱收缩单元维持对抗重力的姿势并驱动对抗惯性的运动。当软组织暴露于单次或反复的生物力学过载时,可能会发生肌肉损伤。肌肉疼痛通常归因于肌筋膜疼痛障碍,这是一种最初由珍妮特·特拉维尔医生和大卫·西蒙斯医生描述的病症。在寻求各种医学专家治疗的患者中,据报道肌筋膜疼痛的发生率在30%至93%之间,具体取决于专科实践和环境。据估计,有4400万美国人患有肌筋膜疼痛;然而,医学专家之间对于肌筋膜疼痛障碍的诊断标准及其作为一种病理实体的存在存在争议。有活动或损伤相关疼痛的肌肉通常会异常缩短,张力增加。此外,肌筋膜疼痛障碍的特征是存在称为触发点的 tender、坚实结节。在每个触发点内有一个超敏点,即“紧张带”,它由过度收缩的梭外肌纤维组成。触压触发点内的这个点会引发向局部参考区域放射的、酸痛型疼痛。研究表明,具有特征性触发点和紧张带的肌筋膜疼痛和功能障碍是由特定脊髓节段持续神经活动的回响回路引起的脊髓反射障碍。肌筋膜疼痛障碍的治疗需要将有症状的触发点和肌肉识别为主要或辅助疼痛源。机械、热和化学治疗,从神经生理学或物理上去除触发点的神经回路,可导致疼痛减轻和肌肉过度收缩的暂时缓解。大多数专家认为,适当的治疗应针对触发点,以恢复正常肌肉长度和肌筋膜元件的正确生物力学取向,随后进行包括对受影响肌肉进行强化和拉伸的治疗。慢性肌筋膜疼痛通常是身体和心理社会影响共同作用的结果,这会使康复复杂化。