Michael Hazar, Fisher Robert S.
Gastroenterology Section, Temple University Hospital, 3401 North Broad Street, Philadelphia, PA 19140, USA.
Curr Treat Options Gastroenterol. 2004 Feb;7(1):41-52. doi: 10.1007/s11938-004-0024-2.
Thoracic esophageal diverticula are uncommon. They account for less than 30% of esophageal diverticula. The majority of patients are asymptomatic or have minimal symptoms. About one third of patients present with severe symptoms. Occasionally, pulmonary symptoms can be the sole manifestation of the disease and can be life threatening. Dysphagia, food regurgitation, chest pain, weight loss, and reflux symptoms are the most commonly encountered gastrointestinal symptoms. Malignancy is a rare complication of esophageal diverticula; therefore, patients should be educated regarding this complication. Appropriate diagnostic tests should be arranged promptly if alarming symptoms develop. Esophageal motor disorders are found in the majority of patients and need to be taken into account when planning therapy. Medical and endoscopic therapies have limited roles in treatment. Surgery is the standard of care for patients with pulmonary or incapacitating symptoms related to an epiphrenic diverticulum, and myotomy is the cornerstone of surgery. To ensure complete relief of the obstruction, the myotomy should extend distally at least 1.5 to 2 cm into the stomach and proximally at least to the neck of diverticulum. Adding a nonobstructing entireflux procedure is recommended to prevent the development of gastroesophageal reflux disease. Occasionally, a specific treatment such as a diverticulectomy or diverticulopexy needs to be directed to the diverticulum. Preliminary treatment results from minimally invasive surgery, especially laparoscopy, have been promising. In the future with increased experience, minimally invasive surgery may become the standard of care.
胸段食管憩室并不常见。它们占食管憩室的比例不到30%。大多数患者无症状或症状轻微。约三分之一的患者有严重症状。偶尔,肺部症状可能是该病的唯一表现,且可能危及生命。吞咽困难、食物反流、胸痛、体重减轻和反流症状是最常见的胃肠道症状。恶性肿瘤是食管憩室罕见的并发症;因此,应就这一并发症对患者进行教育。如果出现警示症状,应及时安排适当的诊断检查。大多数患者存在食管运动障碍,在制定治疗方案时需要考虑到这一点。药物治疗和内镜治疗在治疗中的作用有限。对于有与膈上憩室相关的肺部症状或致残症状的患者,手术是标准的治疗方法,而肌切开术是手术的基石。为确保完全解除梗阻,肌切开术应向远端至少延伸至胃内1.5至2厘米,向近端至少延伸至憩室颈部。建议增加一个无梗阻的全反流手术以预防胃食管反流病的发生。偶尔,需要针对憩室进行特定的治疗,如憩室切除术或憩室固定术。微创手术,尤其是腹腔镜手术的初步治疗效果很有前景。未来随着经验的增加,微创手术可能会成为标准的治疗方法。