Fenollar Florence, Gauduchon Valérie, Casalta Jean-Paul, Lepidi Hubert, Vandenesch François, Raoult Didier
Unité des Rickettsies, Faculté de Médecine, Université de la Méditerranée, and Fédération de Bactériologie, Virologie et Hygiène hospitalière, Hôpital de la Timone, Marseille, France.
Clin Infect Dis. 2004 Feb 1;38(3):e21-4. doi: 10.1086/380839. Epub 2003 Dec 29.
We describe 2 patients with endocarditis for whom blood cultures and cardiac valve cultures were repeatedly sterile. Broad-range eubacterial polymerase chain reaction (PCR) amplification performed on cardiac valve specimens from these 2 patients detected DNA of Mycoplasma hominis, for one patient, and of Ureaplasma parvum, for the other patient. Three other cases of infective endocarditis caused by mycoplasmas were identified in the literature. It is important to rule out a diagnosis of mycoplasma endocarditis because the evolution of the disease may be fatal and it requires an adequate and specific antibiotic therapy.
我们描述了2例心内膜炎患者，其血培养和心脏瓣膜培养多次无菌。对这2例患者的心脏瓣膜标本进行的泛菌属聚合酶链反应（PCR）扩增检测到，其中1例患者的标本中有人型支原体DNA，另1例患者的标本中有微小脲原体DNA。文献中还鉴定出另外3例由支原体引起的感染性心内膜炎病例。排除支原体性心内膜炎的诊断很重要，因为该病的进展可能是致命的，且需要充分且特异的抗生素治疗。
