Hu Jin, Cui Yonghua, Wei Minghui
Department of Otolaryngology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030.
Lin Chuang Er Bi Yan Hou Ke Za Zhi. 2003 Oct;17(10):604-6.
To investigate the expression of inducible nitric oxide synthase(iNOS) in the mucus involved in allergic fungal rhinosinusitis(AFRS) and chronic sinusitis(CRS).
The iNOS expression was examined using immunohistochemistry in cases of AFRS as well as CRS.
The expression rate of iNOS in AFRS was significantly higher than in CRS.
The increased expression of iNOS may involve in AFRS pathogenesis. Statistical difference between AFRS and CRS groups may indicate two groups may be distinct diseases entity.
探讨诱导型一氧化氮合酶（iNOS）在变应性真菌性鼻窦炎（AFRS）和慢性鼻窦炎（CRS）黏液中的表达情况。
采用免疫组织化学法检测AFRS及CRS病例中iNOS的表达。
AFRS中iNOS的表达率显著高于CRS。
iNOS表达增加可能参与AFRS的发病机制。AFRS组与CRS组之间的统计学差异可能表明两组可能是不同的疾病实体。
