Joseph Lavin A, Wright Anita C
Aquatic Food Products Laboratory, Food Science and Human Nutrition Department, University of Florida, Gainesville, Florida 32611, USA.
J Bacteriol. 2004 Feb;186(3):889-93. doi: 10.1128/JB.186.3.889-893.2004.
Vibrio vulnificus is a human pathogen that produces lethal septicemia in susceptible persons, and the primary virulence factor for this organism is capsular polysaccharide (CPS). The role of the capsule in V. vulnificus biofilms was examined under a variety of conditions, by using either defined CPS mutants or spontaneous CPS expression phase variants derived from multiple strains. CPS expression was shown to inhibit attachment and biofilm formation, which contrasted with other studies describing polysaccharides as integral to biofilms in related species.
创伤弧菌是一种可在易感人群中引发致命败血症的人类病原体，该生物体的主要毒力因子是荚膜多糖（CPS）。通过使用特定的CPS突变体或源自多个菌株的自发CPS表达阶段变体，在多种条件下研究了荚膜在创伤弧菌生物膜中的作用。结果表明，CPS表达会抑制附着和生物膜形成，这与其他将多糖描述为相关物种生物膜不可或缺组成部分的研究形成了对比。
