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RNA导入线粒体。

Import of RNA into mitochondria.

作者信息

Schneider A

机构信息

Biozentrum, Department of Biochemistry, University of Basel, CH-4056 Basel, Switzerland.

出版信息

Trends Cell Biol. 1994 Aug;4(8):282-6. doi: 10.1016/0962-8924(94)90218-6.

Abstract

RNAs that function in mitochondria, in contrast to the majority of mitochondrial proteins, are generally encoded by the mitochondrial genome. However, evidence has been presented for transport of nucleus-encoded tRNAs into mitochondria in diverse organisms. While mitochondrial protein import has been characterized in great detail, virtually nothing is known about the pathway of RNA import into mitochondria. Only very recently have in vivo systems for RNA import been established, and these are now providing some insight into this intriguing process.

摘要

与大多数线粒体蛋白质不同,在线粒体中发挥作用的RNA通常由线粒体基因组编码。然而,已有证据表明,在多种生物中,细胞核编码的tRNA可转运至线粒体。虽然线粒体蛋白质的导入已得到详细研究,但对于RNA导入线粒体的途径却几乎一无所知。直到最近才建立了RNA导入的体内系统,这些系统现在为这一有趣的过程提供了一些见解。

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