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慢性阻塞性肺疾病:生命的最后一年

Chronic obstructive pulmonary disease: the last year of life.

作者信息

Hansen-Flaschen John

机构信息

Pulmonary, Allergy, and Critical Care Division, University of Pennsylvania School of Medicine, Philadelphia PA 19104, USA.

出版信息

Respir Care. 2004 Jan;49(1):90-7; discussion 97-8.

Abstract

Nearly one quarter million Americans die with or of advanced chronic obstructive pulmonary disease (COPD) each year. Many patients die after a prolonged functional decline that is accompanied by much suffering. Though difficult prognostically and emotionally, anticipation of death opens the door to planning and preparing for terminal care. Epidemiologists have begun to identify characteristics of COPD patients who are most likely to die within 6-12 months, including severe, irreversible airflow obstruction, severely impaired and declining exercise capacity and performance status, older age, concomitant cardiovascular or other co-morbid disease, and a history of recent hospitalizations for acute care. Clinicians are encouraged to raise the difficult subject of planning for death when many of these characteristics apply. Patients with far-advanced disease are often receptive to the recommendation of a dual agenda: "Hope for and expect the best, and prepare for the worst." Medical advance planning is best pursued in an out-patient office during a prescheduled, 3-way conversation between patient, health care proxy, and physician. An advance directive can be written after the meeting to summarize the conversation. Clinicians should consider recommending hospice care when a COPD patient is at high risk of respiratory failure from the next chest infection and in need of frequent or specialized home care. Preparation for death should include a realistic appraisal of the prospects for dying peacefully at home and a contingency plan for terminal hospitalization, should the need arise.

摘要

每年有近25万美国人死于晚期慢性阻塞性肺疾病(COPD)或因该病死亡。许多患者在长期功能衰退并伴有巨大痛苦后死亡。尽管在预后和情感方面都很困难,但对死亡的预期为临终关怀的规划和准备打开了大门。流行病学家已开始确定最有可能在6至12个月内死亡的COPD患者的特征,包括严重、不可逆的气流阻塞、严重受损且不断下降的运动能力和身体状况、高龄、伴有心血管疾病或其他合并症,以及近期因急性病住院的病史。当出现许多这些特征时,鼓励临床医生提出关于死亡规划这个棘手的话题。患有极晚期疾病的患者通常会接受“抱最好的希望,做最坏的打算”这一双重议程的建议。最佳的医疗预嘱规划是在门诊办公室,由患者、医疗保健代理人和医生进行预先安排的三方谈话时进行。会后可以撰写一份预先指示来总结谈话内容。当COPD患者因下一次胸部感染而有呼吸衰竭的高风险且需要频繁或专门的家庭护理时,临床医生应考虑推荐临终关怀。死亡准备应包括对在家中平静离世前景的现实评估,以及如有需要的临终住院应急计划。

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