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[胆囊结石——总是手术指征吗?]

[Gallbladder calculi--always an indication for surgery?].

作者信息

Bittner R, Ulrich M

机构信息

Klinik für Allgemein- und Viszeralchirurgie, Marienhospital Stuttgart.

出版信息

Internist (Berl). 2004 Jan;45(1):8-15. doi: 10.1007/s00108-003-1105-3.

Abstract

There is consensus that symptomatic cholecystolithiasis presents an indication for cholecystectomy. Today the surgical method of choice is the laparoscopic technique, which has proven its superiority in numerous randomized studies. Epidemiologic studies showed that 10-15% of all gallstone patients develop complications so that a prophylactic cholecystectomy is repeatedly being discussed. A few older studies based on conventional cholecystectomies, however, showed no decisive advantage for a prophylactic cholecystectomy, but rather clearly higher costs. Therefore a wait-and-see policy is generally recommended for asymptomatic gallstones. The analysis of our large group of patients showed that acute cholecystitis as well as common bile duct stones occur significantly more often with increasing duration of the gallstone disease. The older the patient, the longer the operation time, the more frequent a conversion, and the higher the morbidity of the procedure. Considering the minor impairment of daily activities with the laparoscopic technique, the present concept of treatment for asymptomatic and mildly symptomatic cholecystolithiasis needs to be scrutinized.

摘要

目前已达成共识,有症状的胆囊结石是胆囊切除术的指征。如今,首选的手术方法是腹腔镜技术,该技术已在众多随机研究中证明了其优越性。流行病学研究表明,所有胆结石患者中有10% - 15%会出现并发症,因此预防性胆囊切除术一直备受讨论。然而,一些基于传统胆囊切除术的早期研究并未显示预防性胆囊切除术有决定性优势,反而成本明显更高。因此,对于无症状胆结石,一般建议采取观望策略。对我们大量患者的分析表明,随着胆结石疾病病程的延长,急性胆囊炎以及胆总管结石的发生频率显著增加。患者年龄越大,手术时间越长,中转手术的频率越高,手术的发病率也越高。考虑到腹腔镜技术对日常活动的轻微影响,目前无症状和轻度症状胆囊结石的治疗观念需要重新审视。

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