Bovi Mitre Graciela, Kamiya Norma, Bardón Alicia, Asakawa Yoshinori
Facultad de Ingeniería, Universidad Nacional de Jujuy, Gorriti 237, San Salvador de Jujuy 4600, Argentina.
J Nat Prod. 2004 Jan;67(1):31-6. doi: 10.1021/np030074z.
Seven africanes (1, 2a,b, 3-6), two of them new (1, 2a), three secoafricanes (7-9), one of them new (7), and two norsecoafricanes (10, 11a), one of them new (10), all of them swartzianin-type, have been isolated from an Argentine collection of the endemic liverwort Porella swartziana. The structures of the new compounds were established by extensive 1D and 2D NMR spectroscopic data. Absolute configurations of compounds 2a, 2b, and 10 were derived on the basis of CD spectra. The compounds were tested for activity against a variety of microbes, but none were found to exhibit significant antibacterial activity.
从阿根廷产的地方性苔类植物斯氏片叶苔（Porella swartziana）的样本中，分离出了七种非洲紫杉烷型化合物（1、2a、b、3 - 6），其中两种为新化合物（1、2a）；三种裂环非洲紫杉烷型化合物（7 - 9），其中一种为新化合物（7）；以及两种去甲裂环非洲紫杉烷型化合物（10、11a），其中一种为新化合物（10）。所有这些化合物均为施瓦茨宁型。新化合物的结构通过广泛的一维和二维核磁共振光谱数据得以确定。化合物2a、2b和10的绝对构型基于圆二色光谱推导得出。对这些化合物针对多种微生物的活性进行了测试，但未发现有化合物表现出显著的抗菌活性。
