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从樟芝菌丝体中分离得到的五种新型马来酸和琥珀酸衍生物及其对LLC肿瘤细胞系的细胞毒性作用。

Five new maleic and succinic acid derivatives from the mycelium of Antrodia camphorata and their cytotoxic effects on LLC tumor cell line.

作者信息

Nakamura Norio, Hirakawa Akiko, Gao Jiang-Jing, Kakuda Hiroko, Shiro Motoo, Komatsu Yasuhiro, Sheu Chia-chin, Hattori Masao

机构信息

Institute of Natural Medicine, Toyama Medical and Pharmaceutical University, 2630 Sugitani, Toyama 930-0194, Japan.

出版信息

J Nat Prod. 2004 Jan;67(1):46-8. doi: 10.1021/np030293k.

DOI:10.1021/np030293k
PMID:14738384
Abstract

Five new maleic and succinic acid derivatives were isolated from the mycelium of Antrodia camphorata. Their structures were determined by various spectroscopic means. Maleimide derivatives 2 and 3 showed appreciable cytotoxic activity against LLC cells.

摘要

从樟芝菌丝体中分离出五种新的马来酸和琥珀酸衍生物。通过各种光谱手段确定了它们的结构。马来酰亚胺衍生物2和3对LLC细胞显示出明显的细胞毒性活性。

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