Kubota Natsuki K, Ohta Shinji, Ohta Emi, Koizumi Fumito, Suzuki Makoto, Ichimura Michio, Rahayu Endang S, Ikegami Susumu
Instrument Center for Chemical Analysis, Hiroshima University, 1-3-1 Kagamiyama, Higashi-Hiroshima 739-8526, Japan.
J Nat Prod. 2004 Jan;67(1):85-7. doi: 10.1021/np030324b.
Two new beta-hydroxy acetamides, BE-52211 B and BE-52211 C, which were structural analogues of BE-52211, were obtained as an inseparable mixture from an actinomycete, Streptomyces sp. Their structures were elucidated on the basis of spectroscopic data. They inhibited cell division of starfish embryos at a concentration of 2.5 microg/mL or greater.
从链霉菌属放线菌中获得了两种新的β-羟基乙酰胺BE-52211 B和BE-52211 C,它们是BE-52211的结构类似物,以不可分离的混合物形式存在。基于光谱数据阐明了它们的结构。它们在浓度为2.5微克/毫升或更高时可抑制海星胚胎的细胞分裂。