Seidler A, Nienhaus A, Diel R
Institute of Occupational Medicine, Johann Wolfgang Goethe-University, Frankfurt/Main, Germany.
Occup Environ Med. 2004 Feb;61(2):96-102. doi: 10.1136/oem.2003.008573.
This review briefly summarises the recent achievements in tuberculosis epidemiology associated with the introduction of molecular methods, and considers the implications of these methods for the understanding of occupational tuberculosis transmission. Special attention is paid to the relative contribution of recently transmitted tuberculosis; risk factors for recent transmission; and the occurrence and frequency of exogenous reinfection. There is a need for occupational epidemiological studies, which should combine the methods of "classical" epidemiology with those of molecular epidemiology.
本综述简要总结了与分子方法引入相关的结核病流行病学近期成就，并思考了这些方法对理解职业性结核病传播的意义。特别关注近期传播的结核病的相对贡献；近期传播的危险因素；以及外源性再感染的发生情况和频率。需要开展职业流行病学研究，应将“经典”流行病学方法与分子流行病学方法相结合。
