科索沃阿尔巴尼亚人的15个AmpF lSTR Identifiler基因座的群体遗传学
Population genetics of the 15 AmpF lSTR Identifiler loci in Kosovo Albanians.
作者信息
Kubat M, Skavić J, Behluli I, Nuraj B, Bekteshi T, Behluli M, Klarić I Martinović, Pericić M
机构信息
Department of Forensic Medicine and Criminology, University of Zagreb School of Medicine, Salata 11, 10000 Zagreb, Croatia.
出版信息
Int J Legal Med. 2004 Apr;118(2):115-8. doi: 10.1007/s00414-004-0430-y. Epub 2004 Jan 23.
The 15 AmpF lSTR Identifiler loci (D8S1179, D21S11, D7S820, CSF1PO, D3S1358, THO1, D13S317, D16S539, D2S1338, D19S433, VWA, TPOX, D18S51, D5S818 and FGA) were analyzed in a sample of 136 unrelated Albanian adults from Kosovo. The agreement with HWE was confirmed for all loci with the exception of TPOX (based on the exact test only). The combined power of discrimination (PD) and the combined power of exclusion (PE) for the 15 studied loci were 0.99999999999999997 and 0.9999995, respectively. According to the presented data, FGA proved to be the most informative marker. An interpopulation comparison between Kosovo Albanians and Croatians (as an example of a population from the Balkans) revealed significant differences in four out of nine loci.
对来自科索沃的136名无亲缘关系的阿尔巴尼亚成年个体样本进行了15个荧光标记短串联重复序列（AmpF lSTR）基因座（D8S1179、D21S11、D7S820、CSF1PO、D3S1358、THO1、D13S317、D16S539、D2S1338、D19S433、VWA、TPOX、D18S51、D5S818和FGA）的分析。除TPOX基因座外（仅基于确切检验），所有基因座均符合哈迪-温伯格平衡（HWE）。所研究的15个基因座的联合鉴别力（PD）和联合排除力（PE）分别为0.99999999999999997和0.9999995。根据所呈现的数据，FGA被证明是信息含量最高的标记。科索沃阿尔巴尼亚人和克罗地亚人（作为巴尔干半岛人群的一个例子）之间的群体间比较显示，9个基因座中有4个存在显著差异。
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