抗抑郁药的通用处方
Generic prescribing of antidepressants.
作者信息
Bruck P, Antao C A, Henry J A
机构信息
National Poisons Unit, Guy's Hospital, London.
出版信息
J R Soc Med. 1992 Nov;85(11):682-5. doi: 10.1177/014107689208501109.
Analysis of National Health Service prescription data for the antidepressants from 1980 to 1989 shows a consistent secular trend towards the increased use of generic names on prescriptions for this group of drugs. This apparently reflects national trends for all drugs, and was similar for most antidepressants. However, generic prescribing had by 1989 increased significantly more rapidly with fluvoxamine, which was introduced in 1987. The two drugs introduced in 1989, fluoxetine and amoxapine, also had a high generic prescribing rate in their year of introduction. Increased generic prescribing may become a feature with further new drugs. However, the use of the generic name on the prescription has relatively little influence on what is dispensed to the patient. Pharmacists may dispense a brand name when given a generic prescription. Moreover, pressures on doctors to write generic names on prescriptions may have limited relevance for some drugs; generic alternatives were available for only four out of 22 antidepressants.
对1980年至1989年国民医疗服务体系抗抑郁药处方数据的分析显示，在这类药物的处方上，使用通用名的情况呈持续的长期增长趋势。这显然反映了所有药物的全国性趋势，大多数抗抑郁药的情况类似。然而，到1989年，随着1987年引入的氟伏沙明，通用名处方的增长显著加快。1989年引入的两种药物，氟西汀和阿莫沙平，在引入当年的通用名处方率也很高。随着更多新药出现，通用名处方增加可能会成为一种趋势。然而，处方上使用通用名对给患者配药的影响相对较小。当收到通用名处方时，药剂师可能会配发品牌药。此外，要求医生在处方上写通用名的压力对某些药物可能影响有限；22种抗抑郁药中只有4种有通用名替代药。
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