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剖宫产瘢痕部位异位妊娠:一家医疗中心的8年经验

Ectopic pregnancies in Caesarean section scars: the 8 year experience of one medical centre.

作者信息

Maymon R, Halperin R, Mendlovic S, Schneider D, Vaknin Z, Herman A, Pansky M

机构信息

Department of Obstetrics and Gynecology and Institute of Pathology, Assaf Harofe Medical Center, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

出版信息

Hum Reprod. 2004 Feb;19(2):278-84. doi: 10.1093/humrep/deh060.

Abstract

BACKGROUND

Our aim was to supplement the mostly individual case reports on the rarely occurring and life-threatening condition of ectopic pregnancy developing in a Caesarean section scar.

METHODS AND RESULTS

Eight of all the patients treated in our department between 1995 and 2002 had been diagnosed for ectopic pregnancy that developed in a Caesarean section scar. They comprised this case series group. Four of them underwent methotrexate treatment; one had expectant management, one transcervical aspiration of the gestational sac and two by open surgery. All the non-surgically treated women had an uneventful outcome. One underwent a term Caesarean hysterectomy and the other first trimester hysterotomy and excision of the pregnancy located in the scarred uterus. Analysis of all these women's obstetric history revealed that five of them (63%) had been previously operated because of breech presentation, one had a cervical pregnancy and one had placenta previa. Four of them (50%) had multiple (> or = 2) Caesarean sections.

CONCLUSIONS

The women at risk for pregnancy in a Caesarean section scar appear to be those with a history of placental pathology, ectopic pregnancy, multiple Caesarean sections and Caesarean breech delivery. Heightened awareness of this possibility and early diagnosis by means of transvaginal sonography can improve outcome and minimize the need for emergency extended surgery.

摘要

背景

我们的目的是补充关于剖宫产瘢痕处发生罕见且危及生命的异位妊娠的大多为个案报告的资料。

方法与结果

1995年至2002年间在我们科室接受治疗的所有患者中,有8例被诊断为剖宫产瘢痕处异位妊娠。他们组成了这个病例系列组。其中4例接受了甲氨蝶呤治疗;1例进行了期待治疗,1例经宫颈吸取妊娠囊,2例接受了开放手术。所有非手术治疗的女性结局均良好。1例接受了足月剖宫产子宫切除术,另1例在孕早期进行了子宫切开术并切除了瘢痕子宫内的妊娠物。对所有这些女性的产科病史分析显示,其中5例(63%)曾因臀位分娩接受过手术,1例有宫颈妊娠,1例有前置胎盘。其中4例(50%)接受过多次(≥2次)剖宫产。

结论

剖宫产瘢痕处有妊娠风险的女性似乎是那些有胎盘病理史、异位妊娠史、多次剖宫产史和剖宫产臀位分娩史的女性。提高对这种可能性的认识并通过经阴道超声进行早期诊断可以改善结局,并尽量减少紧急扩大手术的必要性。

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