Goodson M L, Vernon B G
School of Population and Health Sciences, The Medical School, University of Newcastle, Newcastle upon Tyne NE2 4HH, UK.
J Clin Pathol. 2004 Feb;57(2):135-8. doi: 10.1136/jcp.2003.9886.
To assess public opinion on the use of tissue samples from living adults and children for clinical research.
A questionnaire study of 100 healthy volunteers (100% response rate) from a Newcastle NHS dental practice. The issues investigated were the types of tissues that individuals were prepared to donate for research, the type of research donors would be prepared to consent to, and attitudes to research on children's tissues.
Eighteen per cent of the participants said that they would not give consent for research to be carried out on their tissues, 50% would not give consent for the donation of a child's tissues. Only 26% of subjects said that they would give consent for research on genetic cloning compared with 82% for cancer research. Sex differences existed in the responses.
Greater research attention needs to be given to public opinion on the use of tissue from living subjects for medical research to facilitate drafting of new legislation.
评估公众对于使用成年活体和儿童的组织样本进行临床研究的意见。
对来自纽卡斯尔国民保健服务牙科诊所的100名健康志愿者进行问卷调查研究（回复率100%）。调查的问题包括个人愿意捐赠用于研究的组织类型、捐赠者愿意同意的研究类型以及对儿童组织研究的态度。
18%的参与者表示他们不会同意对其组织进行研究，50%的人不会同意捐赠儿童组织。只有26%的受试者表示他们会同意进行基因克隆研究，而同意癌症研究的比例为82%。在回复中存在性别差异。
需要更多地关注公众对于使用活体组织进行医学研究的意见，以便于起草新的立法。
