Murphy J K, O'Donohue L
Department of Pathology, West Wales General Hospital, Carmarthenshire NHS Trust, Carmarthen SA31 2A, UK.
J Clin Pathol. 2004 Feb;57(2):139-40. doi: 10.1136/jcp.2003.12104.
To evaluate the use and effectiveness of fungal stains in a dermatopathology service of a district general hospital.
A retrospective analysis of skin biopsies submitted over three years, where fungal stains were used; the results were correlated with clinical history and case notes.
In total, 99 cases were studied for fungi with the periodic acid Schiff stain with diastase. Fungi were present in seven cases; fungi had been suggested in the differential diagnosis of three of these cases but were an unexpected finding in four cases.
Non-specific clinical details should prompt early fungal staining and non-specific microscopic findings or inappropriate well recognised skin reaction patterns should warrant the exclusion of fungal infection. The finding of at least one case of unexpected fungal infection is justified financially and for patient best management where clinical and microscopic findings are non-specific or inappropriate.
评估真菌染色在一家地区综合医院皮肤病理学服务中的应用及效果。
对三年内送检的使用了真菌染色的皮肤活检标本进行回顾性分析；将结果与临床病史和病例记录相关联。
总共对99例病例用高碘酸希夫淀粉酶染色法研究真菌。7例存在真菌；其中3例在鉴别诊断中曾怀疑有真菌，但4例为意外发现。
非特异性临床细节应促使早期进行真菌染色，而非特异性显微镜检查结果或不适当的、公认的皮肤反应模式应排除真菌感染。对于临床和显微镜检查结果非特异性或不适当的情况，发现至少一例意外真菌感染从经济角度以及为患者提供最佳管理方面都是合理的。
