Rao Shalinee, Janaki Amutha, Kamakshi D, Srinivasan V
Department of Pathology, Sri Ramachandra University, Porur, Chennai-600 116, India.
J Cutan Aesthet Surg. 2010 May;3(2):111-4. doi: 10.4103/0974-2077.69025.
Treatment of alopecia is often challenging for the clinician as it includes a spectrum of lesions ranging from congenital to acquired causes. We present three cases of congenital circumscribed alopecia, present since birth, clinically diagnosed as nevus sebaceous. Histopathological examination of the excised tissue showed syringocystadenoma papilliferum with dermatophytosis in one and nevus sebaceous with dermatophytosis in the other two cases. Although complete excision is the treatment of choice for these lesions, an antifungal agent is needed to eradicate the concurrent superficial mycosis. A careful histopathological examination of the lesional skin helps in identifying such unexpected dual lesions that would need further treatment.
对临床医生而言，脱发的治疗往往具有挑战性，因为其涵盖了一系列从先天性到后天性病因的病变。我们呈现三例先天性局限性脱发病例，自出生即存在，临床诊断为皮脂腺痣。切除组织的组织病理学检查显示，其中一例为伴有皮肤癣菌病的乳头状汗管囊腺瘤，另外两例为伴有皮肤癣菌病的皮脂腺痣。尽管这些病变的首选治疗方法是完整切除，但需要使用抗真菌药物来根除并发的浅表真菌病。对病变皮肤进行仔细的组织病理学检查有助于识别此类需要进一步治疗的意外双重病变。
