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一名肝硬化患者发生致命的犬巴斯德菌腹膜炎和败血症:病例报告及文献复习

Fatal Pasteurella dagmatis peritonitis and septicaemia in a patient with cirrhosis: a case report and review of the literature.

作者信息

Ashley B D, Noone M, Dwarakanath A D, Malnick H

机构信息

University Hospital of North Tees, Hardwick, Stockton on Tees TS19 8PE, UK.

出版信息

J Clin Pathol. 2004 Feb;57(2):210-2. doi: 10.1136/jcp.2003.7419.

Abstract

Pasteurella species cause zoonotic infections in humans. Human pasteurella infections usually manifest as local skin or soft tissue infection following an animal bite or scratch. Systemic infections are less common and are limited to patients at the extremes of age or those who have serious underlying disorders, including cirrhosis. Most human pasteurella infections are caused by the multocida species. We report a case of Pasteurella dagmatis peritonitis and septicaemia in a patient with cirrhosis. The infection followed a scratch inflicted by a pet dog. Despite appropriate antibiotic treatment the infection proved fatal. Spontaneous bacterial peritonitis caused by P dagmatis has not been reported previously. Pasteurella dagmatis is a relatively recently described species, which is rarely reported as a human pathogen. This species may be misidentified unless commercial identification systems are supplemented by additional biochemical tests.

摘要

巴斯德氏菌属可引起人类的人畜共患感染。人类巴斯德氏菌感染通常表现为动物咬伤或抓伤后局部皮肤或软组织感染。全身感染较少见,仅限于年龄极端的患者或患有严重基础疾病(包括肝硬化)的患者。大多数人类巴斯德氏菌感染由多杀巴斯德氏菌引起。我们报告一例肝硬化患者发生达氏巴斯德氏菌腹膜炎和败血症的病例。感染是由宠物狗抓伤引起的。尽管进行了适当的抗生素治疗,但感染仍被证明是致命的。此前尚未报道过由达氏巴斯德氏菌引起的自发性细菌性腹膜炎。达氏巴斯德氏菌是一个相对较新描述的菌种,很少被报道为人病原体。除非商业鉴定系统辅以额外的生化试验,否则该菌种可能会被误认。

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