Backman Tiina, Rauramo Ilkka, Huhtala Sakke, Koskenvuo Markku
Department of Obstetrics and Gynecology, University Hospital of Turku, Finland.
Am J Obstet Gynecol. 2004 Jan;190(1):50-4. doi: 10.1016/j.ajog.2003.07.021.
This study was undertaken to evaluate the pregnancy rate with the levonorgestrel intrauterine system (LNG IUS) and to analyze the outcome of pregnancies with the LNG IUS in situ in regular use.
Questionnaires from 17,360 users of the LNG IUS were analyzed. With the consent of women reporting pregnancy during the use of the LNG IUS, related hospital records were reviewed concerning the pregnancies.
Originally 132 pregnancies were reported. Medical records were reviewed from 108 of these women. In 64 pregnancies, conception occurred with the LNG IUS in situ. Thirty-three pregnancies were ectopic. The 5-year cumulative pregnancy rate per 100 users was 0.5 and the 5-year Pearl rate was 0.11.
Pregnancy with the LNG IUS in situ is rare. Ectopic pregnancies constitute 53% of all pregnancies. Typical pregnancy symptoms occur during pregnancies with the LNG IUS. The importance to counsel about the risk of pregnancy before insertion is emphasized.
本研究旨在评估左炔诺孕酮宫内节育系统（LNG IUS）的妊娠率，并分析正常使用LNG IUS期间妊娠的结局。
分析了17360名LNG IUS使用者的问卷。在报告使用LNG IUS期间妊娠的妇女同意下，查阅了与妊娠相关的医院记录。
最初报告了132例妊娠。对其中108名妇女的病历进行了查阅。在64例妊娠中，LNG IUS在位时发生受孕。33例妊娠为异位妊娠。每100名使用者的5年累积妊娠率为0.5，5年Pearl率为0.11。
LNG IUS在位时妊娠罕见。异位妊娠占所有妊娠的53%。使用LNG IUS期间妊娠会出现典型的妊娠症状。强调了在放置前咨询妊娠风险的重要性。
