Chattopadhyay Anindya, Prakash Bhanu, Vepakomma Deepti, Nagendhar Yoga
Department of Pediatric Surgery, Kasturba Medical College, 576119, Manipal, Karnataka, India.
Pediatr Surg Int. 2004 Feb;20(2):127-9. doi: 10.1007/s00383-003-1104-4. Epub 2004 Jan 29.
We prospectively evaluated the safety and efficacy of total gut irrigation (TGI) using normal saline with added potassium (NS) and polyethylene glycol (PG) in patients undergoing a variety of colorectal procedures including single-stage pull-through for Hirschsprung's disease (HD). Fifty-four patients were randomly assigned into one of the two groups (NS or PG). Pre- and post-TGI weight, abdominal girth, and serum electrolytes were assessed. Patients were also evaluated for vomiting and abdominal discomfort. At surgery, bowel preparation was evaluated, and postoperative complications were recorded. Both NS and PG are safe and effective agents for TGI. No patient in either group had any clinical or statistically significant change in the evaluated parameters. The amount of NS required for TGI was significantly higher than PG, and PG was better tolerated than NS. All patients with HD completed TGI, although one patient with long segment HD had abdominal distension.
我们前瞻性评估了在接受包括先天性巨结肠（HD）一期拖出术在内的各种结直肠手术的患者中，使用添加钾的生理盐水（NS）和聚乙二醇（PG）进行全肠道灌洗（TGI）的安全性和有效性。54例患者被随机分为两组（NS组或PG组）之一。评估了TGI前后的体重、腹围和血清电解质。还对患者的呕吐和腹部不适情况进行了评估。在手术时，评估肠道准备情况，并记录术后并发症。NS和PG都是用于TGI的安全有效药物。两组中均没有患者在评估参数上出现任何临床或统计学上的显著变化。TGI所需的NS量显著高于PG，且PG的耐受性优于NS。所有HD患者均完成了TGI，尽管1例长段HD患者出现了腹胀。
