Zimmerman Deena R, Klinger Gil, Merlob Paul
TEREM-Immediate Medical Services, Jerusalem, Macabi Health Services, Shaalvim, Israel.
ScientificWorldJournal. 2003 Dec 18;3:1363-9. doi: 10.1100/tsw.2003.108.
The increased frequency of early discharge of newborns has led to questions of its safety. Most studies have looked at mortality and rehospitalization, not all missed diagnoses. The purpose of this study was to determine diagnoses in newborn infants that would have been missed if the infant had been discharged in <24 h. The design was a cohort study at Rabin Medical Center-Beilinson Campus (average monthly deliveries 1996 [250], 1997 [500]), a university-affiliated community hospital with all in-born term (> or = 37 weeks) infants born September through November 1996 and June 1997. The main outcome measures were medical diagnoses (except trivial physical descriptions) noted at discharge (generally at > or =48 h) exam, not noted on admission exam (<24 h). The results showed that 54 infants (5.1%) had diagnoses that were not detected before the infant was 24 h of age. The leading diagnosis was hyperbilirubinemia. Other potentially missed diagnoses included congenital heart disease (n = 10), morbidity of birth trauma (n = 9), metabolic disturbances (n = 2), hip dislocation (n = 1), suspected sepsis (n = 2), excessive weight loss (n = 2), polycythemia (n = 2), inguinal hernia (n = 1), and abducens paresis (n = 1). It is concluded that diagnoses can be missed by discharging infants in 24 h or less. These diagnoses have the potential for adverse sequela. Even if early discharge is felt to be cost effective, parents should be counseled that it is not risk free. Better mechanisms should be put in place for assuring the safety of such infants.
新生儿早期出院频率的增加引发了对其安全性的质疑。大多数研究关注的是死亡率和再次住院情况,而非所有漏诊情况。本研究的目的是确定如果婴儿在出生后<24小时出院可能会被漏诊的新生儿疾病。研究设计为在拉宾医疗中心 - 贝林森校区(1996年平均每月分娩量为250例,1997年为500例)进行的队列研究,该校区是一家与大学相关的社区医院,纳入了1996年9月至11月以及1997年6月出生的所有足月(≥37周)的院内出生婴儿。主要观察指标为出院时(一般在≥48小时)检查中记录的医学诊断(不包括轻微的身体描述),而入院检查(<24小时)时未记录。结果显示,54名婴儿(5.1%)存在在24小时龄前未被检测出的诊断。主要诊断为高胆红素血症。其他可能漏诊的诊断包括先天性心脏病(n = 10)、产伤并发症(n = 9)、代谢紊乱(n = 2)、髋关节脱位(n = 1)、疑似败血症(n = 2)、体重过度减轻(n = 2)、红细胞增多症(n = 2)、腹股沟疝(n = 1)和外展神经麻痹(n = 1)。结论是,在24小时或更短时间内让婴儿出院可能会导致漏诊。这些诊断有可能产生不良后果。即使早期出院被认为具有成本效益,也应告知家长这并非无风险。应建立更好的机制以确保此类婴儿的安全。